Steve Ottersberg



The purpose of this talk is to provide a physiological basis for understanding the function of the ECS and how genetics and diet influence endocannabinoid tone. From the physiological basis of the ECS this presentation will build upon the pharmacology and pharmacogenomics to provide rationale for determining the most effective clinical approach to endocannabinoid therapies. Polymorphisms in the genes for the component enzymes and receptors of the ECS can influence the clinical outcome of cannabinoid therapies. One poignant example of this are ultra-fast variants of CYP2C9 are poor candidates for oral consumption of Delta-9-THC due to the rapid conversion of Delta-9-THC into 11-OH-THC. 11-OH-THC is poorly tolerated due to intensity of euphoric effect and long terminal plasma half-life (up to 72 hours).

Source

Oils

Capsules

Gummies

Topical

Huckelberry Hard Candy by Billifer’s Recreational Cannabis Review 7KjihoRsDHE
Cannabis Laws in South Africa
Abilene Cannabis Dating
Jon Venus Threatened Me
Can all CBD oil be Vaped?
Huckelberry Hard Candy by Billifer’s Recreational Cannabis Review 7KjihoRsDHE
Recreational Cannabis Review of Blackberry Kush Flower By Purple Planet
Hemp Juice, The Ultimate Immune Boost
Can all CBD oil be Vaped?
Recreational Cannabis Review of Blackberry Kush Flower By Purple Planet
Empowering Self-Service with Communities
Mind Pump Episode #1148
Hemp Juice, The Ultimate Immune Boost
Medical Cannabis Helps Opiate Detox in Cancer Patient
Tesla CEO Elon Musk Smokes Weed During Joe Rogan Podcast
Spirit Animals by Hanna Karlzon using Amazon Basics Pencils Part
FREE Webinar on the Entourage Effect
Cannabis Online Marketing Dos and Don’ts
Top 7 Ways To Use CBD
A Quick One Minute CBD Guide to understand the basics